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(RTTNews) - Immunome, Inc. (IMNM) shares jumped 20.44%, rising $4.00 to close at $23.57, following the company's announcement of positive topline results from its Phase 3 RINGSIDE trial evaluating varegacestat in patients with desmoid tumors.

The Phase 3 study met its primary endpoint, demonstrating a statistically significant and clinically meaningful reduction in tumor volume versus placebo, along with favorable secondary outcomes.

The results position varegacestat as a potential best-in-class oral treatment for this rare and difficult-to-treat condition, and meaningfully de-risk the program ahead of potential regulatory discussions.

IMNM trades within a 52-week range of approximately $7.50 - $25.10.

The sharp move underscores investor optimism around varegacestat's commercial potential and Immunome's transition into a late-stage clinical company with a near-term regulatory catalyst.

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